Surgical relief of left ventricular outflow-tract obstruction by septal myectomy is an effective primary treatment for patients with hypertrophic cardiomyopathy (HCM). The procedure substantially ...

WASHINGTON, DC—A transcatheter electrosurgical procedure that mimics surgical myotomy may be an option in some patients to relieve left ventricular outflow tract (LVOT) obstruction in the setting of ...

Pre- and perinatal diagnosis and the rapid availability of cord blood for stem cells have resulted in a subset of very young patients undergoing stem cell transplantation. There are several ...

To the Editor: In the article by Maron et al. (Jan. 23 issue) 1 about the effect of left ventricular outflow tract obstruction on the clinical outcome in hypertrophic cardiomyopathy, the authors ...

Patients with obstructive hypertrophic cardiomyopathy (HCM) who took an investigational agent that targets cardiac myosin over about 7 months showed across-the-board improvements in functional ...

The U.S. Food and Drug Administration has approved Myqorzo (aficamten) for the treatment of adults with symptomatic ...

Daniel L. Jacoby, Eugene C. DePasquale and William J. McKenna Hypertrophic cardiomyopathy is a common inherited cardiomyopathy, occurring in about 1 in 500 individuals.1 The first gene mutation for ...

Hypertrophic cardiomyopathy is an underdiagnosed genetic disorder, resulting from mutations in sarcomeric proteins. It has a highly variable clinical presentation, with some individuals remaining ...

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ACCURATE diagnosis of obstruction to the outflow tract from the left ventricle was not considered necessary until the development of extracorporeal circulation and open-heart surgery. The diagnosis of ...