Study uncovers key insights about how a new class of antiviral drugs works. Cryo-EM images showed the drugs bound to herpes simplex virus (HSV) protein at nearly atomic detail, while optical tweezers ...

Aptamer Group plc, a developer of synthetic oligonucleotide-based binding reagents for life sciences applications, and ...

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human genome, together with protein-coding sequences,” said Donate Weghorn, a ...

ABSTRACT: The aim of a present study is to perform a brief but clear comparison of numerous and controversial data published in the past 20 years which were focusing on the significance of structural ...

Gear-obsessed editors choose every product we review. We may earn commission if you buy from a link. Why Trust Us? Without 8 or 9 hours of sleep, most of us end up staggering around like zombies. But ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mitochondrial DNA (mtDNA) replication is ...

Freshly isolated hearts and mesenteric resistance arteries from all of the groups were immediately frozen in liquid nitrogen and then homogenized in ice-cold lysis buffer, as described previously.

Patch-clamp recordings demonstrated that LHON neurons, which typically exhibit impaired sodium and potassium currents, showed restored electrophysiological function after co-culture with MSCs.

A common hallmark of viral genome replication is a high mutation rate, which can aid in their ability to evade new treatments and acquire resistance to once-effective antiviral medications. Now, a new ...