Continuing 5-ASA after escalation to advanced therapy in ulcerative colitis is associated with lower odds of clinical remission.

A recent randomised controlled trial showed that proton pump inhibitors (PPIs), compared with histamine-2 receptor antagonists (H2RAs), induce greater gut microbiome alterations and oral-to-gut ...

Investigational rosnilimab was safe and well-tolerated; however, it did not meet the primary endpoint of the mean change from baseline in the modified Mayo Score (severity of ulcerative colitis, mMS) ...

Affecting around five to 10 million people worldwide, ulcerative colitis (UC) is a long-term inflammatory disease that causes the gut lining to become swollen and develop ulcers. It leads to ongoing ...

CAR T-cell therapy was first developed as a lymphoma treatment but has recently been applied to autoimmune diseases, primarily lupus, systemic sclerosis, and myositis. Up to this point, ulcerative ...

For decades, scientists have puzzled over why smoking makes Crohn’s disease worse but seems to protect people from ulcerative colitis. Now, researchers at RIKEN have discovered that smoking creates ...

Earlier reports blamed several medications including nonsteroidal anti-inflammatory drugs (NSAIDs), proton pump inhibitors (PPIs), selective serotonin reuptake inhibitors (SSRIs), statins, and ...

You’ve probably heard the adage “an apple a day keeps the doctor away.” But the opposite can actually be true if you have ulcerative colitis (UC), an inflammatory bowel disease (IBD) that causes ...

Colitis and ulcerative colitis (UC) can look very similar because they share symptoms like abdominal pain, diarrhea, and bloody stool, and they both involve inflammation of the colon (the large ...

Ischemic Colitis occurs when blood flow to part of the colon is reduced or blocked, causing inflammation and potential tissue damage. Symptoms can range from mild abdominal discomfort to severe pain ...

Ulcerative Colitis (UC) is a chronic inflammatory bowel disease affecting the colon lining, and its incidence is rising globally, especially in industrialized countries. The causes of UC are complex ...