BMJ Evidence-Based Medicine

Methylphenidate denied access to WHO’s list of essential medicines for the third time

Attention-deficit/hyperactivity disorder (ADHD) affects 3%–5% of children and about 2.5% of adults, though prevalence varies ...
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Using and distinguishing evidence from non-randomised studies of interventions

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EBHC pyramid 5.0 for accessing preappraised evidence and guidance

Correspondence to: Dr Brian S Alper, DynaMed, EBSCO Health, 10 Estes Street, Ipswich, MA 01938, USA; balper{at}ebsco.com Practising evidence-based healthcare (EBHC) is integrating the best research ...
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Online First

Toward automating GRADE classification: a proof-of-concept evaluation of an artificial intelligence-based tool for semiautomated evidence quality rating in systematic reviews ...
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Methylphenidate for ADHD rejected from the WHO Essential Medicines List due to uncertainties in benefit-harm profile

Attention deficit hyperactivity disorder (ADHD) is a common psychiatric disorder with estimated global prevalence rates between 3% and 5% in children and 2.5% in adults, depending on the ...
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Adapt or die: how the pandemic made the shift from EBM to EBM+ more urgent

Evidence-based medicine (EBM’s) traditional methods, especially randomised controlled trials (RCTs) and meta-analyses, along with risk-of-bias tools and checklists, have contributed significantly to ...
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Rapid access to innovative medicinal products while ensuring relevant health technology assessment. Position of the French National Authority for Health

Correspondence to Doctor Antoine Vanier, Health Technology Assessment Department, Haute Autorité de Santé, La Plaine Saint-Denis, 93210, France; a.vanier{at}has-sante.fr In France, decisions for ...
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Network meta-analysis: the highest level of medical evidence?

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Reporting and methodological quality of studies that use Mendelian randomisation in UK Biobank: a meta-epidemiological study

Objectives To identify whether Mendelian randomisation (MR) studies are appropriately conducted and reported in enough detail for other researchers to accurately replicate and interpret them. Design ...
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Reducing the environmental impact of healthcare to improve health, sustainability and equity

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Wrong guidelines: why and how often they occur

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Opportunities, challenges and risks of using artificial intelligence for evidence synthesis

4 Institute of Medical Biometry and Statistics (IMBI), Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany 5 Eye Center, Medical Center, Faculty of Medicine, University of ...