With an increasingly profound understanding of the interplay between condensate biology and diseases, there is a poised acceleration of classical drug development processes, catalyzing breakthroughs ...

A research group has developed a novel and highly accessible technology for producing uniform biomolecular condensates using a simple, low-cost vibration platform. The study is published in the ...

First-in-class condensate-modulating small molecule Development Candidate targeting pathogenic TDP-43 condensates.Restores global TDP-43 splicing ...

A team of researchers led by HHMI Investigator Michael Rosen has captured the most detailed images yet of the molecules in synthetic chromatin condensates — droplet-like structures of compacted DNA.