Diagnosing and treating Crohn’s disease as early as possible can help prevent or stave off serious complications like perianal Crohn’s disease and colon cancer.

As scientists question the rise in early colon cancer cases, a new study is offering some potential answers. Colored scanning electron micrograph (SEM) of a macrophage white blood cell (center) that ...

PALI-2108 is the first and only PDE4 inhibitor in development designed for targeted delivery to the terminal ileum and colon, addressing ...

In patients with Crohn’s Disease, achieving intestinal ultrasound transmural healing is linked to improved long-term outcomes ...

Background Intestinal fibrosis, a hallmark complication of Crohn’s disease (CD), frequently progresses to stricture formation and surgical intervention. Fibroblast metabolic reprogramming is important ...

What Is Crohn’s Constipation? You likely have constipation if it's hard for you to poop and you're having fewer bowel movements than you normally do. The same is true whether or not you have Crohn’s ...

Patients with colon cancer using GLP-1 receptor agonists (the class of drugs behind treatments like Ozempic, Wegovy, and Mounjaro) had substantially lower five-year death rates than those not using ...

Intestinal fibrosis is a common and serious complication of inflammatory bowel diseases, often leading to strictures that require endoscopic or surgical intervention. Despite advances in ...

A diet rich in the amino acid cysteine may have rejuvenating effects in the small intestine, according to a new study from MIT. This amino acid, the researchers discovered, can turn on an immune ...

Background: Reliable predictors of surgical risk in Crohn’s disease (CD) with small bowel stenosis are lacking. Longitudinal CT enterography (CTE) derived body composition parameters may improve risk ...