Researchers expand human genome map to 2.37 million regulatory DNA elements

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...
Harvard Medical School

Researchers Now Understand How a New Class of Antivirals Works

Members of a new class of antivirals are being tested in U.S. clinical trials, and one has gained approval in Japan, but how ...
eLife

Fragile nucleosomes are essential for RNA Polymerase II to transcribe in eukaryotes

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...
Science Daily

This CRISPR breakthrough turns genes on without cutting DNA

A new CRISPR breakthrough shows scientists can turn genes back on without cutting DNA, by removing chemical tags that act ...
EurekAlert!

There are new antivirals being tested for herpesviruses. Scientists now know how they work

Study uncovers key insights about how a new class of antiviral drugs works. Cryo-EM images showed the drugs bound to herpes simplex virus (HSV) protein at nearly atomic detail, while optical tweezers ...