The American Heart Association’s 2025 Adult Basic Life Support Guidelines build upon prior versions with updated recommendations for assessment and management of persons with cardiac arrest, as well ...

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Brain cells begin to die in less than five minutes without oxygen. CPR must start within two minutes when cardiac arrest happens. After nine minutes without oxygen, there is likely severe brain damage ...

Coronary perfusion pressure (CPP) is the measure of blood flow to the heart. Low CPP can mean the heart is not getting enough blood, which can lead to heart damage. During CPR, a CPP of at least 15 ...