Understanding the role of linear ubiquitination in T-tubule biogenesis

Transverse tubules (T-tubules) play a significant role in muscle contraction. However, the underlying mechanism of their ...

Baseball Hall of Fame ballot: Ryan Braun, Edwin Encarnación, Alex Gordon and the other one-and-done candidates

In parts of 14 MLB seasons, Gordon hit .257/.338/.410 (102 OPS+) with 1,643 hits, 357 doubles, 190 home runs, 749 RBI, 867 runs and 113 steals. He's 52nd in JAWS among left fielders.

Madrigal Expands its MASH Pipeline with Exclusive Global License Agreement for Ervogastat, a Phase 2 Oral DGAT-2 Inhibitor

Detailed price information for Madrigal Pharmaceuticals Inc (MDGL-Q) from The Globe and Mail including charting and trades.
Major League Baseball

Venn: Explaining my 2026 Hall of Fame ballot

The responsibility as a first-time voter for the National Baseball Hall of Fame is obviously one I take seriously, and one that requires careful consideration of each candidate. Some were easy and ...

Commentary: Recovering the first right in the Declaration of Independence

The right to life is the most basic because without life, the rights to liberty and the pursuit of happiness are meaningless.
Fierce Biotech

Madrigal pays $50M for Pfizer MASH drug with eye on Rezdiffra combo potential

Madrigal has paid Pfizer $50 million for the rights to a DGAT2i inhibitor with the intention of combining the drug with its ...
eLife

Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles

HIV hijacks SRRM2 to enlarge nuclear speckles, stabilizing CPSF6 puncta and promoting efficient viral replication.