During protein synthesis, the genetic information stored in DNA is first transcribed into mRNA. The mRNA then travels to the ribosome, where translation occurs. Here's how anticodons facilitate the ...

Adeno-associated virus (AAV) is the most successful platform for gene therapy delivery, but offers limited cargo size and can give rise to off-target toxicity. Now, a study in Nature reports the ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

Gene editing can repair mutations that prematurely halt protein synthesis, resulting in incomplete peptides that cause various diseases. However, other approaches achieve the same effect without ...

Alltrna is advancing a new class of genetic medicines based on the power of tRNA biology to universally treat Stop Codon Disease, which encompasses thousands of genetic diseases caused by a premature ...

BOSTON--(BUSINESS WIRE)--hC Bioscience, a biopharmaceutical company developing a fundamentally novel approach to treating genetic diseases through tRNA-based protein editing, today presented ...