Origami is the ancient Japanese art of paper folding. One uncut square of paper can, in the hands of an origami artist, be folded into a bird, a frog, a sailboat, or a Japanese samurai helmet beetle.

In Rothemund’s method, a long strand of DNA snakes back and forth until it forms a desired shape. The key to getting the DNA to form this way, and to holding it in place, are short “staples” of DNA ...