Linear mixed models (LMMs) are a powerful and established tool for studying genotype–phenotype relationships. A limitation of the LMM is that the model assumes Gaussian distributed residuals, a ...

Figure 1: A GWAS for a simulated trait with two causal SNPs randomly chosen from a real A. thaliana SNP data set. GWAS data were simulated by adding phenotypic effects to real genotypic data from A.