The nonlinear cost function may reflect the fact that the cell has limited resources, so that production of Lac proteins reduces the capacity to produce other important proteins. For example, rapidly ...

This is a preview. Log in through your library . Abstract A protein possessing both lac repressor and β -galactosidase activities in a single polypeptide of about 155,000 daltons was purified from a ...

Examples abound in nature in which organisms adapt and optimize their fitness in a given environment. A new study demonstrates that a cellular cost-benefit analysis drives growth optimization over the ...

A fluorescence method was developed to study DNA-protein interactions in solution. A 32-base-pair (bp) DNA fragment of the lac promoter containing the primary binding site for Escherichia coli cAMP ...