Pharmacogenomic Strategies Provide a Rational Approach to the Treatment of Cisplatin-Resistant Patients With Advanced Cancer We used immunohistochemistry to assess histone 3 lysine 4 dimethylation ...

Histone modification is an epigenetic mechanism that regulates gene expression by altering chromatin structure and DNA accessibility for transcription. Histone modification is regulated by various ...

A research team has made a breakthrough in epigenetic drug discovery. The researchers have successfully developed a ...

Molecular biologists decode the epigenetic silencing of problematic retroviral gene sequences. LMU molecular biologist Gunnar Schotta decodes the epigenetic silencing of problematic retroviral gene ...

Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone modification (called “writers,” “erasers,” ...

In a groundbreaking advancement for cancer treatment, a research team led by Professor Xiang David Li from the Department of Chemistry at The University of Hong Kong (HKU) has made significant strides ...

Epigenetics, the study of changes in gene function that do not involve alterations to the DNA sequence, plays a pivotal role in understanding the complex interplay between genetics and the environment ...

A new study has decoded how pea plants respond to salt stress through precise epigenetic reprogramming. Researchers created the first genome-wide map of four major histone modifications—H3K4me3, ...

In a recent study published in the journal Science Advances, a group of researchers investigated the role of histone modifications in human aging by developing and evaluating histone-specific age ...