Researchers at the University of Calgary are running a clinical trial to find out whether a cheap, widely available form of ...

If a prescribed antidepressant does not relieve symptoms, a healthcare professional may increase a person’s dose or change medications. However, sometimes antidepressants that once helped symptoms ...

Wegovy HD, a higher-dose version of the popular weight loss drug, is available. Here's how it compares to standard Wegovy, ...

For patients who receive heart-sparing radiotherapy for breast cancer, coronary artery dose is key in the risk for future cardiac events.

Body surface area-dosing does not account for the complex processes of cytotoxic drug elimination. This leads to an unpredictable variation in effect. Overdosing is easily recognised but it is ...

Many oral drugs show a high variability in pharmacokinetic exposure, and, for drugs with exposure related to efficacy, therapeutic drug monitoring can help optimize exposure in individual patients.

Jessica was a writer on the Wellness team, with a focus on health technology, eye care, nutrition and finding new approaches to chronic health problems. But this potency hinges on the fact we take the ...

Cytarabine (ara-C) is an important drug in the treatment of acute myeloid leukemia (AML). High-dose cytarabine (2000 to 3000 mg per square meter of body-surface area) is toxic but results in higher ...

An experimental gene-editing therapy that aims to lower bad cholesterol for the long-term after a single infusion is off to a positive start in an early clinical trial. Researchers running a Phase I ...

“The dose makes the poison” is an adage credited to Paracelsus, a Swiss physician-philosopher from the early Renaissance. Basically, it means that any substance can become toxic if given at a high ...